Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats

Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats

Cell-based transplantation strategies possess great potential for spinal cord injury (SCI) repair. Basic fibroblast growth factor (bFGF) has been reported to have multiple neuro-promoting effects on developing and adult nervous system of mammals and considered a promising therapy for nerve injury fo...

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Bibliographic Details
Main Authors: Sipin Zhu, Yibo Ying, Yan He, Xingxing Zhong, Jiahui Ye, Zhiyang Huang, Min Chen, Qiuji Wu, Yifan Zhang, Ziyue Xiang, Yurong Tu, Weiyang Ying, Jian Xiao, Xiaokun Li, Qingsong Ye, Zhouguang Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-08-01
Series:Bioactive Materials
Subjects:
Spinal cord injury
Adeno-associated virus
Basic fibroblast growth factor
Dental pulp stem cell
Vascular regulation
Hypoxic microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000347

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http://www.sciencedirect.com/science/article/pii/S2452199X21000347

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