Identifying Network Motifs that Buffer Front-to-Back Signaling in Polarized Neutrophils

Identifying Network Motifs that Buffer Front-to-Back Signaling in Polarized Neutrophils

Neutrophil polarity relies on local, mutual inhibition to segregate incompatible signaling circuits to the leading and trailing edges. Mutual inhibition alone should lead to cells having strong fronts and weak backs or vice versa. However, analysis of cell-to-cell variation in human neutrophils rev...

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Bibliographic Details
Main Authors: Yanqin Wang, Chin-Jen Ku, Elizabeth R. Zhang, Alexander B. Artyukhin, Orion D. Weiner, Lani F. Wu, Steven J. Altschuler
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001769

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http://www.sciencedirect.com/science/article/pii/S2211124713001769

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