Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC)

Background Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius ‘break’ at 43 °C. An alternative method centered on the actual time–temperature plot during each hyperthermia...

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Bibliographic Details
Main Authors: Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer, Stephan Bodis
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:International Journal of Hyperthermia
Subjects:
auc
cem
Online Access:http://dx.doi.org/10.1080/02656736.2021.1875060