Tissue distribution of residual antimony in rats treated with multiple doses of meglumine antimoniate

Meglumine antimoniate (MA) and sodium stibogluconate are pentavalent antimony (SbV) drugs used since the mid-1940s. Notwithstanding the fact that they are first-choice drugs for the treatment of leishmaniases, there are gaps in our knowledge of their toxicological profile, mode of action and kinetic...

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Bibliographic Details
Main Authors: Deise Riba Coelho, Elaine Silva Miranda, Tatiana Dillenburg Saint?Pierre, Francisco José Roma Paumgartten
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014-07-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000400420&lng=en&tlng=en