New Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound

New Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound

Platelet activation plays a major role in cardio and cerebrovascular diseases, and cancer progression. Disruption of platelet activation represents an attractive therapeutic target for reducing the bidirectional cross talk between platelets and tumor cells. Platinum (Pt) compounds have been used for...

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Bibliographic Details
Main Authors: Chih-Wei Hsia, Marappan Velusamy, Jeng-Ting Tsao, Chih-Hsuan Hsia, Duen-Suey Chou, Thanasekaran Jayakumar, Lin-Wen Lee, Jiun-Yi Li, Joen-Rong Sheu
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
Ir(III)-derived complex
platelet activation
protein kinases
OH· free radical
bleeding time
pulmonary thromboembolism
Online Access:https://www.mdpi.com/1422-0067/18/12/2616

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https://www.mdpi.com/1422-0067/18/12/2616

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