Capacity of the medullary cavity of tibia and femur for intra-bone marrow transplantation in mice.

Intra-bone marrow transplantation (IBMT) has been adapted for mouse models to improve the seeding efficiency of transplanted hematopoietic stem and progenitor cells. Commonly used injection volumes for IBMT into the tibia differ between 10 and 40 μL even though considerable amounts of injected cells...

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Bibliographic Details
Main Authors: Dieter Fink, Ulrike Pfeiffenberger, Tina Bernthaler, Sophie Schober, Kerstin E Thonhauser, Thomas Rülicke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224576