Working memory performance correlates with prefrontal-hippocampal theta interactions but not with prefrontal neuron firing rates

Performance of memory tasks is impaired by lesions to either the medial prefrontal cortex (mPFC) or the hippocampus (HPC); although how these two areas contribute to successful performance is not well understood. mPFC unit activity is temporally affected by hippocampal theta oscillations, with almos...

Full description

Bibliographic Details
Main Authors: James M Hyman, Eric A Zilli, Amanda M Paley, Michael E Hasselmo
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-03-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.07.002.2010/full