Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients

Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients

Osteosarcoma is one among the most common neoplasms in dogs. Current treatments show limited efficacy and fail to prevent metastasis. Conditionally replicative adenoviruses (CRAd) replicate exclusively in targeted tumor cells and release new virus particles to infect additional cells. We proposed th...

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Bibliographic Details
Main Authors: Payal Agarwal, Elizabeth A. Gammon, Maninder Sandey, Stephanie S. Lindley, Jey W. Koehler, Brad M. Matz, Annette N. Smith, Elena A. Kashentseva, Igor P. Dmitriev, David T. Curiel, Bruce F. Smith
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Heliyon
Subjects:
Dog
Cancer
Osteosarcoma
Tumor immunology
Canine adenovirus type 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021003157

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http://www.sciencedirect.com/science/article/pii/S2405844021003157

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