Viscosupplementation may preserve tibial cartilage and collagen in osteoarthritis: findings from a preclinical model of osteoarthritis

Abstract Purpose Intraarticular (IA) hyaluronic acid (HA) injection is used to reduce pain and improve mobility in knee osteoarthritis (OA). Little is known about histopathological changes underlying HA efficacy. This study investigated dose-related effects of 1% sodium hyaluronate (BioHA) on knee j...

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Bibliographic Details
Main Authors: John Lokhnauth, Kevin E. Driscoll, Alison Bendele, Faizan Niazi, Alfred Liang, Crilles C. Larsen
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40634-020-00256-4