Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses

Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses

Peste des Petits Ruminants Virus (PPRV) is an extremely infective morbillivirus that primarily affects goats and sheep. In underdeveloped countries where livestock are the main economical resource, PPRV causes considerable economic losses. Protective live attenuated vaccines are currently available...

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Bibliographic Details
Main Authors: Francesca Macchi, José Manuel Rojas, Andrea Elizabeth Verna, Noemí Sevilla, Valentina Franceschi, Giulia Tebaldi, Sandro Cavirani, Verónica Martín, Gaetano Donofrio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
BoHV-4
PPRV
DIVA vaccines
H antigen
viral vaccines
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00421/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00421/full

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