The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets – improving meta-analysis and prediction of prognosis

<p>Abstract</p> <p>Background</p> <p>The number of gene expression studies in the public domain is rapidly increasing, representing a highly valuable resource. However, dataset-specific bias precludes meta-analysis at the raw transcript level, even when the RNA is from...

Full description

Bibliographic Details
Main Authors: Pepper Stuart D, Okoniewski Michal J, Hey Yvonne, Smethurst Graeme J, Sims Andrew H, Howell Anthony, Miller Crispin J, Clarke Robert B
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/1/42