Alternative (backdoor) androgen production and masculinization in the human fetus.

Alternative (backdoor) androgen production and masculinization in the human fetus.

Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis...

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Bibliographic Details
Main Authors: Peter J O'Shaughnessy, Jean Philippe Antignac, Bruno Le Bizec, Marie-Line Morvan, Konstantin Svechnikov, Olle Söder, Iuliia Savchuk, Ana Monteiro, Ugo Soffientini, Zoe C Johnston, Michelle Bellingham, Denise Hough, Natasha Walker, Panagiotis Filis, Paul A Fowler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000002

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https://doi.org/10.1371/journal.pbio.3000002

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