Neuroendocrine regulation of fat metabolism by autophagy gene atg‐18 in C. elegans dauer larvae

In environments with limited food and high population density, Caenorhabditis elegans larvae may enter the dauer stage, in which metabolism is shifted to fat accumulation to allow larvae to survive for months without food. Mutations in the insulin‐like receptor gene daf‐2 force C. elegans to constit...

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Bibliographic Details
Main Authors: Ray Jia, Jiuli Zhang, Kailiang Jia
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12708