Fecal Microbiota Transplant Mitigates Adverse Outcomes Seen in Patients Colonized With Multidrug-Resistant Organisms Undergoing Allogeneic Hematopoietic Cell Transplantation

Fecal Microbiota Transplant Mitigates Adverse Outcomes Seen in Patients Colonized With Multidrug-Resistant Organisms Undergoing Allogeneic Hematopoietic Cell Transplantation

The gut microbiome can be adversely affected by chemotherapy and antibiotics prior to hematopoietic cell transplantation (HCT). This affects graft success and increases susceptibility to multidrug-resistant organism (MDRO) colonization and infection. We performed an initial retrospective analysis of...

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Bibliographic Details
Main Authors: Andrew J. Innes, Benjamin H. Mullish, Rohma Ghani, Richard M. Szydlo, Jane F. Apperley, Eduardo Olavarria, Renuka Palanicawandar, Edward J. Kanfer, Dragana Milojkovic, Julie A. K. McDonald, Eimear T. Brannigan, Mark R. Thursz, Horace R. T. Williams, Frances J. Davies, Julian R. Marchesi, Jiří Pavlů
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
antimicrobial resistance
multidrug resistant bacteria
gut microbiota
fecal microbiota transplant
hematopoietic (Stem) cell transplantation (HCT)
hematological malignances
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.684659/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.684659/full

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