Effect of Sublethal Prenatal Endotoxaemia on Murine Placental Transport Systems and Lipid Homeostasis

Effect of Sublethal Prenatal Endotoxaemia on Murine Placental Transport Systems and Lipid Homeostasis

Infection alters the expression of transporters that mediate the placental exchange of xenobiotics, lipids and cytokines. We hypothesized that lipopolysaccharide (LPS) modifies the expression of placental transport systems and lipid homeostasis. LPS (150 μg/kg; i.p.) treatments were administered for...

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Bibliographic Details
Main Authors: Mila W. Reginatto, Klaus Novaes Fontes, Victoria R. S. Monteiro, Natalia L. Silva, Cherley Borba Vieira Andrade, Hanailly Ribeiro Gomes, Guinever E. Imperio, Flavia Fonseca Bloise, George Eduardo Gabriel Kluck, Georgia Correa Atella, Stephen G. Matthews, Enrrico Bloise, Tania M. Ortiga-Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
lipopolysaccharide
ATP binding cassette transporters
P-glycoprotein
breast cancer resistance protein
cholesterol
ABC sub-family G member 1
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.706499/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.706499/full

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