Divergent Synthesis of Novel Five-Membered Heterocyclic Compounds by Base-Mediated Rearrangement of Acrylamides Derived from a Novel Isocyanide-Based Multicomponent Reaction

Divergent Synthesis of Novel Five-Membered Heterocyclic Compounds by Base-Mediated Rearrangement of Acrylamides Derived from a Novel Isocyanide-Based Multicomponent Reaction

We have recently reported a novel multicomponent reaction between arylacetic acids and isocyanides, affording α-acyloxyacrylamides through an unusual mechanism. The products of this novel multicomponent reaction can rearrange to five membered heterocyclic compounds when exposed to an alkaline enviro...

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Bibliographic Details
Main Authors: Renata Riva, Andrea Basso, Luca Banfi
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Molecules
Subjects:
multicomponent reactions
isocyanides
rearrangement reactions
diversity oriented synthesis
Online Access:http://www.mdpi.com/1420-3049/16/10/8775/

Internet

http://www.mdpi.com/1420-3049/16/10/8775/

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