Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4.

BACKGROUND:Treatment of breast cancer patients with distant metastases represents one of the biggest challenges in today's gynecological oncology. Therefore, a better understanding of mechanisms promoting the development of metastases is of paramount importance. The serine/threonine kinase AKT...

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Bibliographic Details
Main Authors: Astrid Grottke, Florian Ewald, Tobias Lange, Dominik Nörz, Christiane Herzberger, Johanna Bach, Nicole Grabinski, Lareen Gräser, Frank Höppner, Björn Nashan, Udo Schumacher, Manfred Jücker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4704820?pdf=render