A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit <i>Candida albicans</i> Biofilms

A Selective Serotonin Reuptake Inhibitor, a Proton Pump Inhibitor, and Two Calcium Channel Blockers Inhibit <i>Candida albicans</i> Biofilms

Biofilms formed by the human fungal pathogen <i>Candida albicans</i> are naturally resistant to many of the antifungal agents commonly used in the clinic. We screened a library containing 1600 clinically tested drug compounds to identify compounds that inhibit <i>C. albicans</i&...

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Bibliographic Details
Main Authors: Clarissa J. Nobile, Craig L. Ennis, Nairi Hartooni, Alexander D. Johnson, Matthew B. Lohse
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Microorganisms
Subjects:
drug repurposing
high-throughput screens
biofilms
biofilm inhibition
biofilm disruption
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/2076-2607/8/5/756

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https://www.mdpi.com/2076-2607/8/5/756

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