Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats

Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats

Abstract Background Age-related bone loss plays a vital role in the development of osteoporosis and osteoporotic fracture. Bone marrow stromal cell (BMSC) senescence is highly associated with osteoporosis and limits the application of BMSCs in regenerative medicine. Hypoxia is an essential component...

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Bibliographic Details
Main Authors: Lingxian Yi, Yue Ju, Ying He, Xiushan Yin, Ye Xu, Tujun Weng
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Bone loss
Bone marrow stromal cells
Hypoxia
Aging
Desferal®
Online Access:https://doi.org/10.1186/s13287-020-02112-9

Internet

https://doi.org/10.1186/s13287-020-02112-9

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