In Fungal Intracellular Pathogenesis, Form Determines Fate
For pathogenic microbes to survive ingestion by macrophages, they must subvert powerful microbicidal mechanisms within the phagolysosome. After ingestion, Candida albicans undergoes a morphological transition producing hyphae, while the surrounding phagosome exhibits a loss of phagosomal acidity.For...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2018-10-01
|
| Series: | mBio |
| Subjects: | |
| Online Access: | https://doi.org/10.1128/mBio.02092-18 |