AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Summary: Relapse in acute myeloid leukemia (AML) may result from variable genetic origins or convergence on common biological processes. Exploiting the specificity and sensitivity of regulatory DNA, we analyze patient samples of multiple clinical outcomes covering various AML molecular subtypes. We...

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Bibliographic Details
Main Authors: Caroline R.M. Wiggers, Mirna L. Baak, Edwin Sonneveld, Edward E.S. Nieuwenhuis, Marije Bartels, Menno P. Creyghton
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719310459