Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.

Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.

Accumulating evidence suggests that IL-9-mediated immunity plays a fundamental role in control of intestinal nematode infection. Here we report a different impact of Foxp3⁺ regulatory T cells (Treg) in nematode-induced evasion of IL-9-mediated immunity in BALB/c and C57BL/6 mice. Infection with Stro...

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Bibliographic Details
Main Authors: Birte Blankenhaus, Martina Reitz, Yannick Brenz, Marie-Luise Eschbach, Wiebke Hartmann, Irma Haben, Tim Sparwasser, Jochen Huehn, Anja Kühl, Thorsten B Feyerabend, Hans-Reimer Rodewald, Minka Breloer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24516385/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24516385/pdf/?tool=EBI

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