TNF receptor associated factor 1 (TRAF1) is a major target of soluble TWEAK

TNF receptor associated factor 1 (TRAF1) is a major target of soluble TWEAK

Soluble tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), in contrast to membrane TWEAK and TNF, is only a weak activator of the classical NF-kappaB pathway. We observed that soluble TWEAK was regularly more potent than TNF with respect to the induction of TNF receptor associated f...

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Bibliographic Details
Main Authors: José Antonio Carmona Arana, Axel eSeher, Manfred eNeumann, Isabell eLang, Daniela eSiegmund, Harald eWajant
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Immunology
Subjects:
TNF Receptor-Associated Factor 1
TNF
NF-KappaB
TWEAK
Fn14
CD40 signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00063/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00063/full

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