Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

Mycobacterium bovis Bacille Calmette-Guééérin (BCG) is the only licensed vaccine against tuberculosis (TB), yet its moderate efficacy against pulmonary TB calls for improved vaccination strategies. Mucosal BCG vaccination generates superior protection against TB in animal models; however, the mec...

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Bibliographic Details
Main Authors: Carolina Perdomo, Ulrike Zedler, Anja A. Kuhl, Laura Lozza, Philippe Saikali, Leif E. Sander, Alexis Vogelzang, Stefan H. E. Kaufmann, Andreas Kupz
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e01686-16

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http://mbio.asm.org/cgi/content/full/7/6/e01686-16

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