Allopurinol partially prevents disuse muscle atrophy in mice and humans

Allopurinol partially prevents disuse muscle atrophy in mice and humans

Abstract Disuse muscle wasting will likely affect everyone in his or her lifetime in response to pathologies such as joint immobilization, inactivity or bed rest. There are no good therapies to treat it. We previously found that allopurinol, a drug widely used to treat gout, protects muscle damage a...

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Bibliographic Details
Main Authors: Beatriz Ferrando, Mari Carmen Gomez-Cabrera, Andrea Salvador-Pascual, Carlos Puchades, Frederic Derbré, Arlette Gratas-Delamarche, Ludovic Laparre, Gloria Olaso-Gonzalez, Miguel Cerda, Enrique Viosca, Ana Alabajos, Vicente Sebastiá, Angel Alberich-Bayarri, Fabio García-Castro, Jose Viña
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21552-1

Internet

https://doi.org/10.1038/s41598-018-21552-1

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