The Neuropeptides Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Control HIV-1 Infection in Macrophages Through Activation of Protein Kinases A and C

The Neuropeptides Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Control HIV-1 Infection in Macrophages Through Activation of Protein Kinases A and C

Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are highly similar neuropeptides present in several tissues, endowed with immunoregulatory functions and other systemic effects. We previously reported that both neuropeptides reduce viral production i...

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Bibliographic Details
Main Authors: Jairo R. Temerozo, Suwellen S. D. de Azevedo, Daniella B. R. Insuela, Rhaíssa C. Vieira, Pedro L. C. Ferreira, Vinícius F. Carvalho, Gonzalo Bello, Dumith Chequer Bou-Habib
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
HIV-1
vasoactive intestinal peptide
pituitary adenylate cyclase-activating polypeptide
neuropeptides
macrophages
protein kinase C
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01336/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01336/full

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