25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice.

25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice.

Recent clinical evidence supports a link between 25-hydroxyvitamin D insufficiency (serum 25-hydroxyvitamin D [25(OH)D] levels <30 ng/mL) and Parkinson's disease. To investigate the effect of 25(OH)D depletion on neuronal susceptibility to toxic insult, we induced a state of 25(OH)D deficien...

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Bibliographic Details
Main Authors: E Danielle Dean, Lydia M Mexas, Natalie L Cápiro, Jeanne E McKeon, Mahlon R DeLong, Kurt D Pennell, Jonathan A Doorn, Vin Tangpricha, Gary W Miller, Marian L Evatt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3388077?pdf=render

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http://europepmc.org/articles/PMC3388077?pdf=render

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