Role of yes-associated protein in resistance of HER2+ breast cancer to lapatinib

Objective To construct a lapatinib-resistant breast cancer cell line, and to study the role and underlying mechanism of yes-associated protein (YAP) in Hippo signaling pathway in the process. Methods The drug-resistant cell model of human breast cancer was established by gradually increasing the dos...

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Bibliographic Details
Main Authors: CHEN Peng, XU Ting, GUO Dan, HUANG Jiayi
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-04-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201911189.htm