Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia.

<h4>Background</h4>Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients. This trial was conducted in 2004 to evaluate the safety and effectiveness of CD and comparison with artemether-lumefantr...

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Main Authors: Samuel Dunyo, Giorgio Sirugo, Sanie Sesay, Cyrille Bisseye, Fanta Njie, Majidah Adiamoh, Davis Nwakanma, Mathurin Diatta, Ramatoulie Janha, Fatou Sisay Joof, Beth Temple, Paul Snell, David Conway, Robert Walton, Yin Bun Cheung, Paul Milligan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21666744/?tool=EBI