The Effect of Albumin on MRP2 and BCRP in the Vesicular Transport Assay.

The ABC transporters multidrug resistance associated protein 2 (MRP2) and breast cancer resistance protein (BCRP) are of interest in drug development, since they affect the pharmacokinetics of several drugs. Membrane vesicle transport assays are widely used to study interactions with these proteins....

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Bibliographic Details
Main Authors: Feng Deng, Noora Sjöstedt, Heidi Kidron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5051865?pdf=render