Identification of new splice sites used for generation of rev transcripts in human immunodeficiency virus type 1 subtype C primary isolates.

The HIV-1 primary transcript undergoes a complex splicing process by which more than 40 different spliced RNAs are generated. One of the factors contributing to HIV-1 splicing complexity is the multiplicity of 3' splice sites (3'ss) used for generation of rev RNAs, with two 3'ss, A4a...

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Bibliographic Details
Main Authors: Elena Delgado, Cristina Carrera, Paloma Nebreda, Aurora Fernández-García, Milagros Pinilla, Valentina García, Lucía Pérez-Álvarez, Michael M Thomson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281843?pdf=render