Overexpression of OCT-1 gene is a biomarker of adverse prognosis for diffuse large B-cell lymphoma (DLBCL): data from a retrospective cohort of 77 Brazilian patients

Overexpression of OCT-1 gene is a biomarker of adverse prognosis for diffuse large B-cell lymphoma (DLBCL): data from a retrospective cohort of 77 Brazilian patients

Abstract Background OCT-1 gene is a member of the POU-homeodomain family of transcriptional regulators of B-lymphocyte differentiation by controlling expression of B-cell specific genes. BCL-2 gene is a potent inhibitor of apoptosis and it is essential during B-cell differentiation into germinal cen...

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Bibliographic Details
Main Authors: Gisele R. Gouveia, Suzete C. Ferreira, Sheila A. C. Siqueira, Luis Alberto de Pádua Covas Lage, Abrahão E. Hallack Neto, Renata de Oliveira Costa, Juliana Pereira
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Diffuse large B-cell lymphoma (DLBCL)
OCT-1 gene
BCL-2 gene
Prognosis
Immunochemotherapy
Online Access:http://link.springer.com/article/10.1186/s12885-020-07553-2

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http://link.springer.com/article/10.1186/s12885-020-07553-2

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