Quantitative Trait Locus Analysis Implicates CD4⁺/CD44high Memory T Cells in the Pathogenesis of Murine Autoimmune Pancreatitis.

The mouse strain MRL/MpJ is prone to spontaneously develop autoimmune pancreatitis (AIP). To elucidate the genetic control towards the development of the phenotype and to characterize contributions of immunocompetent cell types, MRL/MpJ mice were interbred with three additional strains (BXD2/TYJ, NZ...

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Bibliographic Details
Main Authors: Julia Bischof, Sarah Müller, Luise Borufka, Farahnaz Asghari, Steffen Möller, Stephanie-Anna Holzhüter, Horst Nizze, Saleh M Ibrahim, Robert Jaster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4556487?pdf=render