Increased Glycolysis and Higher Lactate Production in Hyperglycemic Myotubes

Increased Glycolysis and Higher Lactate Production in Hyperglycemic Myotubes

Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial function and glycolytic rate were evaluated. Further, we examined the intr...

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Bibliographic Details
Main Authors: Jenny Lund, D. Margriet Ouwens, Marianne Wettergreen, Siril S. Bakke, G. Hege Thoresen, Vigdis Aas
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
hyperglycemia
myotubes
glycolysis
lactate
substrate oxidation
pathway analysis
Online Access:https://www.mdpi.com/2073-4409/8/9/1101

Internet

https://www.mdpi.com/2073-4409/8/9/1101

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