Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.

Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defects.

Heterozygous LIS1 mutations are the most common cause of human lissencephaly, a human neuronal migration defect, and DCX mutations are the most common cause of X-linked lissencephaly. LIS1 is part of a protein complex including NDEL1 and 14-3-3ε that regulates dynein motor function and microtubule d...

Full description

Bibliographic Details
Main Authors: Tiziano Pramparo, Ondrej Libiger, Sonia Jain, Hong Li, Yong Ha Youn, Shinji Hirotsune, Nicholas J Schork, Anthony Wynshaw-Boris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3053345?pdf=render

Internet

http://europepmc.org/articles/PMC3053345?pdf=render

Similar Items