Integrative analysis of transcriptome-wide association study and gene expression profiling identifies candidate genes associated with stroke

Background Stroke is a major public health burden worldwide. Although genetic variation is known to play a role in the pathogenesis of stroke, the specific pathogenic mechanisms are still unclear. Transcriptome-wide association studies (TWAS) is a powerful approach to prioritize candidate risk genes...

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Bibliographic Details
Main Authors: Jian Yang, Bin Yan, Yajuan Fan, Lihong Yang, Binbin Zhao, Xiaoyan He, Qingyan Ma, Wei Wang, Ling Bai, Feng Zhang, Xiancang Ma
Format: Article
Language:English
Published: PeerJ Inc. 2019-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7435.pdf