Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis

Summary: Tuberculosis claims >1 million lives annually, and its causative agent Mycobacterium tuberculosis is a highly successful pathogen. Protein kinase B (PknB) is reported to be critical for mycobacterial growth. Here, we demonstrate that PknB-depleted M. tuberculosis can replicate normally a...

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Bibliographic Details
Main Authors: Obolbek Turapov, Francesca Forti, Baleegh Kadhim, Daniela Ghisotti, Jad Sassine, Anna Straatman-Iwanowska, Andrew R. Bottrill, Patrick J. Moynihan, Russell Wallis, Philippe Barthe, Martin Cohen-Gonsaud, Paul Ajuh, Waldemar Vollmer, Galina V. Mukamolova
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314190