Fatty Acid Amides Synthesized from Andiroba Oil (<i>Carapa guianensis</i> Aublet.) Exhibit Anticonvulsant Action with Modulation on GABA-A Receptor in Mice: A Putative Therapeutic Option

Fatty Acid Amides Synthesized from Andiroba Oil (<i>Carapa guianensis</i> Aublet.) Exhibit Anticonvulsant Action with Modulation on GABA-A Receptor in Mice: A Putative Therapeutic Option

Epilepsy is a chronic neurological disease characterized by excessive neuronal activity leading to seizure; about 30% of affected patients suffer from the refractory and pharmacoresistant form of the disease. The anticonvulsant drugs currently used for seizure control are associated with adverse rea...

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Bibliographic Details
Main Authors: Fábio Rodrigues de Oliveira, Keuri Eleuterio Rodrigues, Moisés Hamoy, Ícaro Rodrigues Sarquis, Akira Otake Hamoy, Maria Elena Crespo Lopez, Irlon Maciel Ferreira, Barbarella de Matos Macchi, José Luiz Martins do Nascimento
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceuticals
Subjects:
seizures
pentylenetetrazole
electrocorticographic recordings
biocatalysis
palmitoylethanolamide
Online Access:https://www.mdpi.com/1424-8247/13/3/43

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https://www.mdpi.com/1424-8247/13/3/43

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