Redox-Responsive Manganese Dioxide Nanoparticles for Enhanced MR Imaging and Radiotherapy of Lung Cancer

Redox-Responsive Manganese Dioxide Nanoparticles for Enhanced MR Imaging and Radiotherapy of Lung Cancer

In this study, we synthesized manganese dioxide nanoparticles (MnO2 NPs) stabilized with biocompatible polymers (polyvinylpyrrolidone and polyacrylic acid) and analyzed their effect on non-small cell lung cancer (NSCLC) cells with or without gefitinib resistance in vitro. MnO2 NPs showed glutathione...

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Bibliographic Details
Main Authors: Mi Hyeon Cho, Eun-Seok Choi, Sehee Kim, Sung-Ho Goh, Yongdoo Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Chemistry
Subjects:
manganese dioxide nanoparticles
glutathione
lung cancer
gefitinib
radiotherapy
magnetic resonance imaging
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2017.00109/full

Internet

http://journal.frontiersin.org/article/10.3389/fchem.2017.00109/full

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