EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm

The Ezh2 gene encodes a histone methyltransferase of the polycomb repressive complex 2 that methylates histone H3 lysine 27. In this study, we investigated whether EZH2 has a role in the development of the pharyngeal apparatus and whether it regulates the expression of the Tbx1 gene, which encodes a...

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Bibliographic Details
Main Authors: Cinzia Caprio, Gabriella Lania, Marchesa Bilio, Rosa Ferrentino, Li Chen, Antonio Baldini
Format: Article
Language:English
Published: The Company of Biologists 2021-03-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/14/3/dmm046789