Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa

The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-kDa protein whose structure and proper locali...

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Bibliographic Details
Main Authors: Charlotte Lombardi, James Tolchard, Stephanie Bouillot, Luca Signor, Caroline Gebus, David Liebl, Daphna Fenel, Jean-Marie Teulon, Juliane Brock, Birgit Habenstein, Jean-Luc Pellequer, Eric Faudry, Antoine Loquet, Ina Attrée, Andréa Dessen, Viviana Job
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
type III secretion system
Pseudomonas aeruginosa
T3SS needle
structure
virulence
immunofluorescence microscopy
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00573/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00573/full

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