Non-syndromic Cleft Lip and Palate Polymorphisms Affect Normal Lip Morphology

Non-syndromic cleft lip with or without palate (NSCL/P) is a frequent malformation of the facial region. Genetic variants (SNPs) within nineteen loci have been previously associated with NSCL/P in GWAS studies of European individuals. These common variant SNPs may have subtler effects on the morphol...

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Bibliographic Details
Main Authors: Caryl Wilson-Nagrani, Stephen Richmond, Lavinia Paternoster
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00413/full