Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS.

Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS.

<h4>Background</h4>Risk models (RM) need external validation to assess their value beyond the setting in which they were developed. We validated a RM combining mpMRI and clinical parameters for the probability of harboring significant prostate cancer (sPC, Gleason Score ≥ 3+4) for biopsy...

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Bibliographic Details
Main Authors: Jan Philipp Radtke, Francesco Giganti, Manuel Wiesenfarth, Armando Stabile, Jose Marenco, Clement Orczyk, Veeru Kasivisvanathan, Joanne Nyaboe Nyarangi-Dix, Viktoria Schütz, Svenja Dieffenbacher, Magdalena Görtz, Albrecht Stenzinger, Wilfried Roth, Alex Freeman, Shonit Punwani, David Bonekamp, Heinz-Peter Schlemmer, Markus Hohenfellner, Mark Emberton, Caroline M Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221350

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https://doi.org/10.1371/journal.pone.0221350

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