AA-NAT, MT1 and MT2 Correlates with Cancer Stem-Like Cell Markers in Colorectal Cancer: Study of the Influence of Stage and p53 Status of Tumors

AA-NAT, MT1 and MT2 Correlates with Cancer Stem-Like Cell Markers in Colorectal Cancer: Study of the Influence of Stage and p53 Status of Tumors

The characterization of colon cancer stem cells (CSCs) may help to develop novel diagnostic and therapeutic procedures. p53 loss increases the pool of CSCs in colorectal cancer (CRC). Recent reports suggest that the oncostatic effects of melatonin could be related to its ability to kill CSCs. Althou...

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Bibliographic Details
Main Authors: Jorge Casado, Almudena Iñigo-Chaves, Sergio M. Jiménez-Ruiz, Sandra Ríos-Arrabal, Ángel Carazo-Gallego, Cristina González-Puga, María Isabel Núñez, Ángeles Ruíz-Extremera, Javier Salmerón, Josefa León
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal cancer
melatonin
cancer stem cells
p53
metastasis
Online Access:http://www.mdpi.com/1422-0067/18/6/1251

Internet

http://www.mdpi.com/1422-0067/18/6/1251

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