Non-canonical Binding Site for Bacterial Initiation Factor 3 on the Large Ribosomal Subunit

Canonical translation initiation in bacteria entails the assembly of the 30S initiation complex (IC), which binds the 50S subunit to form a 70S IC. IF3, a key initiation factor, is recruited to the 30S subunit at an early stage and is displaced from its primary binding site upon subunit joining. We...

Full description

Bibliographic Details
Main Authors: Akanksha Goyal, Riccardo Belardinelli, Marina V. Rodnina
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
IF3
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312731