Glucose-6-phosphate dehydrogenase mutations in malaria endemic area of Thailand by multiplexed high‐resolution melting curve analysis

Glucose-6-phosphate dehydrogenase mutations in malaria endemic area of Thailand by multiplexed high‐resolution melting curve analysis

Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common enzymopathy in humans, is prevalent in tropical and subtropical areas where malaria is endemic. Anti-malarial drugs, such as primaquine and tafenoquine, can cause haemolysis in G6PD-deficient individuals. Hence,...

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Bibliographic Details
Main Authors: Usa Boonyuen, Duantida Songdej, Sasipa Tanyaratsrisakul, Suparat Phuanukoonnon, Kamonwan Chamchoy, Aun Praoparotai, Phonchanan Pakparnich, Sirapapha Sudsumrit, Thomas Edwards, Christopher T. Williams, Rachel L. Byrne, Emily R. Adams, Mallika Imwong
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Malaria Journal
Subjects:
G6PD deficiency
G6PD mutations
High-resolution melting
Phenotype
G6PD enzyme activity
G6PD genotype
Online Access:https://doi.org/10.1186/s12936-021-03731-0

Internet

https://doi.org/10.1186/s12936-021-03731-0

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