Leishmania donovani Nucleoside Hydrolase terminal domains in cross-protective immunotherapy against Leishmania amazonensis murine infection

Leishmania donovani Nucleoside Hydrolase terminal domains in cross-protective immunotherapy against Leishmania amazonensis murine infection

Nucleoside hydrolases of the Leishmania genus are vital enzymes for the replication of the DNA and conserved phylogenetic markers of the parasites. Leishmania donovani Nucleoside hydrolase (NH36) induced a main CD4+ T cell driven protective response against Leishmania chagasi infection in mice which...

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Bibliographic Details
Main Authors: Dirlei eNico, Daniele Crespo Gomes, Iam ePalatnik-de-Sousa, Alexandre eMorrot, Marcos ePalatnik, Clarisa B. Palatnik-De-Sousa
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
Visceral leishmaniasis
cutaneous leishmaniasis
diffuse cutaneous leishmaniasis
cross-immunotherapy
Nucleoside hydrolases
recombinant vaccines
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00273/full

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http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00273/full

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