Preparation and characterization of different liposomal formulations containing P5 HER2/neu-derived peptide and evaluation of their immunological responses and antitumor effects

Preparation and characterization of different liposomal formulations containing P5 HER2/neu-derived peptide and evaluation of their immunological responses and antitumor effects

Objective(s):Tumor-associated antigen (TAA) subunit-based vaccines constitute promising tools for anticancer immunotherapy. However, a major limitation in the development of such vaccines is the poor immunogenicity of peptides when used alone.The aim of this study was to develop an efficient vaccine...

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Bibliographic Details
Main Authors: Sheida Shariat, Ali Badiee, Seyed Amir Jalali, Mercedeh Mansourian, Seyed Alireza Mortazavi, Mahmoud Reza Jaafari
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Breast cancer
CTL epitope
HER2/neu peptide
Peptide vaccine
pH-sensitive liposome
Online Access:http://ijbms.mums.ac.ir/pdf_4415_05b59658a23ebad6f4e498ffb765b187.html

Internet

http://ijbms.mums.ac.ir/pdf_4415_05b59658a23ebad6f4e498ffb765b187.html

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