Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.

Functional mutation of multiple solvent-exposed loops in the Ecballium elaterium trypsin inhibitor-II cystine knot miniprotein.

<h4>Background</h4>The Ecballium elaterium trypsin inhibitor (EETI-II), a 28-amino acid member of the knottin family of peptides, contains three interwoven disulfide bonds that form multiple solvent-exposed loops. Previously, the trypsin binding loop of EETI-II has been engineered to con...

Full description

Bibliographic Details
Main Authors: Richard H Kimura, Douglas S Jones, Lei Jiang, Zheng Miao, Zhen Cheng, Jennifer R Cochran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364742/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21364742/?tool=EBI

Similar Items