Genetic Abnormalities in Biliary Brush Samples for Distinguishing Cholangiocarcinoma from Benign Strictures in Primary Sclerosing Cholangitis

Background. Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease and is strongly associated with cholangiocarcinoma (CCA). The lack of efficient diagnostic methods for CCA is a major problem. Testing for genetic abnormalities may increase the diagnostic value of cytology. Met...

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Bibliographic Details
Main Authors: Margriet R. Timmer, Chiu T. Lau, Sybren L. Meijer, Paul Fockens, Erik A. J. Rauws, Cyriel Y. Ponsioen, Silvia Calpe, Kausilia K. Krishnadath
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/4381513